Primary Identifier | MGI:3619363 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 723848 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; miRNA-mediated post-transcriptional gene silencing; and sensory perception of sound. Is expressed in several structures, including brain; branchial arch; sensory organ; skin; and somite. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human MIR34A (microRNA 34a). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal neuroprogenitor cell proliferation in the subventricular zone or increased reprogramming efficiency of mouse embryonic fibroblasts. [provided by MGI curators] |