| Primary Identifier | MGI:1101059 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 21942 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables signaling receptor activity. Acts upstream of or within regulation of immature T cell proliferation in thymus. Predicted to be located in external side of plasma membrane. Is expressed in renal vasculature. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human TNFRSF9 (TNF receptor superfamily member 9). PHENOTYPE: Homozygous mutation of this gene results in enhanced T cell proliferation, decreased B cell IgG production, decreased cytotoxic T cell activity, and increased numbers of erythrocytes, granulocyte macrophages, and multipotential progenitor cells in the bone marrow, blood, and spleen. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
