| Primary Identifier | MGI:1277134 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 18628 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables kinase binding activity and ubiquitin protein ligase binding activity. Involved in regulation of circadian sleep/wake cycle, sleep. Acts upstream of or within circadian rhythm and negative regulation of transcription by RNA polymerase II. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; and oocyte. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome; advanced sleep phase syndrome 3; and bipolar disorder. Orthologous to human PER3 (period circadian regulator 3). PHENOTYPE: Mice homozygous for a targeted null mutation exhibit a shorter circadian cycle length. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
