Primary Identifier | MGI:1321389 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 22319 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable SNAP receptor activity and syntaxin-1 binding activity. Involved in SNARE complex assembly; positive regulation of receptor recycling; and substrate adhesion-dependent cell spreading. Acts upstream of or within several processes, including Golgi to plasma membrane protein transport; calcium-ion regulated exocytosis; and cellular response to type II interferon. Located in several cellular components, including cell surface; cytoplasmic vesicle; and perinuclear region of cytoplasm. Is expressed in several structures, including adrenal gland; brain; and gonad. Orthologous to human VAMP3 (vesicle associated membrane protein 3). PHENOTYPE: Homozygotes for a targeted null mutation lack vesicle-associated membrane protein 3 but are apparently normal. [provided by MGI curators] |