| Primary Identifier | MGI:1917275 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 70025 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity and long-chain fatty acyl-CoA hydrolase activity. Acts upstream of or within fatty acid catabolic process. Located in several cellular components, including cytosol; mitochondrial matrix; and neuronal cell body. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human ACOT7 (acyl-CoA thioesterase 7). PHENOTYPE: Mice homozygous for a floxed allele activated in neurons exhibit abnormal glucose and lipid homeostasis, altered metabolism, increaased adiposity, decreased lean mass, progressive neurodegeneration, and neurological defects in aged mice. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
