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Protein Coding Gene : Ajap1 adherens junction associated protein 1

Primary Identifier  MGI:2685419 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  230959
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables protein domain specific binding activity. Predicted to be involved in negative regulation of cell-matrix adhesion; negative regulation of wound healing; and regulation of polarized epithelial cell differentiation. Predicted to be located in basolateral plasma membrane and cell surface. Predicted to be active in adherens junction; cell-cell contact zone; and cytoplasmic side of plasma membrane. Is expressed in several structures, including adrenal gland; brain; eye; genitourinary system; and spinal cord. Orthologous to human AJAP1 (adherens junctions associated protein 1).
PHENOTYPE: Mice homozygous for a null allele exhibit normal response to baclofen-induced reduction of evoked EPSC amplitude. [provided by MGI curators]
  • synonyms:
  • Ajap1,
  • Gm573,
  • gene model 573, (NCBI),
  • adherens junction associated protein 1,
  • LOC230959

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

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3 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

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Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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0 Driver For