| Primary Identifier | MGI:104876 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 15208 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in several processes, including negative regulation of cell differentiation; nephron morphogenesis; and regulation of DNA-templated transcription. Acts upstream of or within several processes, including nervous system development; regulation of nervous system development; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; paraxial mesenchyme; sensory organ; and urinary system. Orthologous to human HES5 (hes family bHLH transcription factor 5). PHENOTYPE: Mice homozygous for disruptions in this gene are phenotypically normal although there are subtile histological abnormalities associated with sensory organs. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
