Primary Identifier | MGI:1914763 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 67513 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and ubiquitin-modified protein reader activity. Predicted to be involved in interstrand cross-link repair and translesion synthesis. Predicted to be located in cell junction; chromatin; and nuclear body. Predicted to be part of Fanconi anaemia nuclear complex. Is expressed in several structures, including genitourinary system; immune system; liver; lung; and muscle tissue. Orthologous to human FAAP20 (FA core complex associated protein 20). PHENOTYPE: Homozygous null mice show seminiferous tubule and ovarian follicle degeneration, small litter sizes, and increased sensitivity to DNA crosslinkers. [provided by MGI curators] |