| Primary Identifier | MGI:1931051 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 57741 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including nucleosome binding activity; p53 binding activity; and transcription corepressor activity. Predicted to be involved in several processes, including cellular response to UV; negative regulation of apoptotic process; and negative regulation of transcription by RNA polymerase II. Predicted to be located in chromosome; cytosol; and nucleus. Predicted to be part of Noc1p-Noc2p complex; Noc2p-Noc3p complex; and nucleosome. Predicted to be active in nucleolus and nucleoplasm. Is expressed in several structures, including connective tissue; eye; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human NOC2L (NOC2 like nucleolar associated transcriptional repressor). PHENOTYPE: Mice lacking expression of this gene display embryonic lethality prior to the tooth bud stage. Mice with an immune cell deletion display impaired T and B cell differentiation with a cell cycle defect. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
