Primary Identifier | MGI:2446220 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 231004 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; identical protein binding activity; and protein domain specific binding activity. Involved in retinal rod cell development. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Part of PRC1 complex. Is expressed in photoreceptor layer; pineal gland; retina; retina layer; and retina outer nuclear layer. Orthologous to human SAMD11 (sterile alpha motif domain containing 11). PHENOTYPE: Mice homozygous for a null allele are viable and show no gross abnormalities. [provided by MGI curators] |