Primary Identifier | MGI:3704243 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 208595 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables sequence-specific DNA binding activity. Acts upstream of or within transcription initiation at mitochondrial promoter. Located in mitochondrion. Orthologous to human MTERF1 (mitochondrial transcription termination factor 1). PHENOTYPE: Mice homozygous for a knock-out allele of both Mterf1a and Mterf1b exhibit impaired transcription initiation at light-strand promoters resulting in a decrease of de novo transcription and reduced 7S RNA. [provided by MGI curators] |