Primary Identifier | MGI:1921364 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 74114 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables carnitine O-octanoyltransferase activity. Involved in carnitine metabolic process; coenzyme A metabolic process; and fatty acid metabolic process. Acts upstream of or within fatty acid transport. Located in peroxisome. Is expressed in several structures, including brain; ganglia; gut; liver; and spleen. Orthologous to human CROT (carnitine O-octanoyltransferase). PHENOTYPE: Mice homozygous for a null allele exhibit normal gross anatomy. Mice homozygous for a null allele and Ldlr null allele exhibit reduced arterial calcification without alteration in bone density. [provided by MGI curators] |