Primary Identifier | MGI:1860118 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 108151 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chemorepellent activity; neuropilin binding activity; and semaphorin receptor binding activity. Predicted to be involved in several processes, including axon guidance; neural crest cell migration; and semaphorin-plexin signaling pathway. Located in extracellular space. Is expressed in several structures, including alimentary system; foot mesenchyme; intraembryonic coelom; nervous system; and sensory organ. Orthologous to human SEMA3D (semaphorin 3D). PHENOTYPE: Mice homozygous for a knock-out allele exhibit pulmonary vein connection to the right atrium and atrial septal defect. [provided by MGI curators] |