| Primary Identifier | MGI:107557 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 20348 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables semaphorin receptor binding activity. Involved in several processes, including cardiac endothelial to mesenchymal transition; chordate embryonic development; and circulatory system development. Acts upstream of or within several processes, including blood vessel remodeling; dichotomous subdivision of terminal units involved in salivary gland branching; and neural crest cell migration. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and respiratory system. Orthologous to human SEMA3C (semaphorin 3C). PHENOTYPE: Mice homozygous for an ENU mutation exhibit perinatal lethality, hypopigmentation and abnormal heart development. Mice homozygous for a knock-out allele exhibit prenatal lethality associated with heart defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
