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Protein Coding Gene : Napepld N-acyl phosphatidylethanolamine phospholipase D

Primary Identifier  MGI:2140885 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  242864
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables N-acylphosphatidylethanolamine-specific phospholipase D activity. Involved in several processes, including N-acylphosphatidylethanolamine metabolic process; host-mediated regulation of intestinal microbiota composition; and positive regulation of brown fat cell differentiation. Acts upstream of or within N-acylethanolamine metabolic process. Is active in hippocampal mossy fiber to CA3 synapse; smooth endoplasmic reticulum membrane; and synaptic membrane. Orthologous to human NAPEPLD (N-acyl phosphatidylethanolamine phospholipase D).
PHENOTYPE: Mice homozygous for a null mutation are viable and healthy, but have abnormal brain levels of N-acyl ethanolamines and N-acyl phosphatidylethanolamines. [provided by MGI curators]
  • synonyms:
  • AB112350,
  • cDNA sequence AB112350,
  • NAPE-PLD,
  • Napepld,
  • N-acyl phosphatidylethanolamine phospholipase D

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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0 Driver For