| Primary Identifier | MGI:1924825 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 69188 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including histone H3K4 methyltransferase activity; methylated histone binding activity; and transcription coactivator activity. Involved in several processes, including erythrocyte differentiation; neutrophil activation; and neutrophil mediated immunity. Predicted to be located in euchromatin and nuclear body. Predicted to be part of Rpd3L-Expanded complex and Set3 complex. Is expressed in several structures, including alimentary system; eye; heart; metanephros; and nervous system. Human ortholog(s) of this gene implicated in autistic disorder and cervical cancer. Orthologous to human KMT2E (lysine methyltransferase 2E (inactive)). PHENOTYPE: Mice homozygous for a null allele exhibit neonatal and postnatal lethality, reduced fertility and growth, and abnormal lymphopoiesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
