| Primary Identifier | MGI:2183446 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 213990 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GTPase activity and polyubiquitin modification-dependent protein binding activity. Acts upstream of or within cellular response to reactive oxygen species; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein import into nucleus. Located in cell periphery; cytoplasm; and nucleus. Is expressed in cerebral cortex subventricular zone; cerebral cortex ventricular layer; and cortical plate. Orthologous to human AGAP3 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 3). PHENOTYPE: Mice homozygous for a null allele exhibit postnatal lethality and hyperactivity. Mice homozygous for a conditional allele activated in the dorsal forebrain exhibit immature dentate gyrus. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
