| Primary Identifier | MGI:1914243 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 66993 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including nuclear receptor binding activity; nuclear receptor coactivator activity; and transcription coregulator binding activity. Involved in neural retina development. Acts upstream of or within heart morphogenesis; muscle cell differentiation; and positive regulation of DNA-templated transcription. Located in nucleus. Part of SWI/SNF complex; nBAF complex; and npBAF complex. Is expressed in several structures, including brain; genitourinary system; gut; sensory organ; and spinal cord. Orthologous to human SMARCD3 (SWI/SNF related BAF chromatin remodeling complex subunit D3). PHENOTYPE: Mice homozygous for a null allele exhibit die around E12.5-E14.5, depending on background, exhibit various cardiac defects including hemorrhage, dilated heart, abnormal interventricular septum development, and impaired heart physiology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
