| Primary Identifier | MGI:1100509 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 16527 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable S100 protein binding activity and potassium channel activity. Involved in detection of hypoxic conditions in blood by carotid body chemoreceptor signaling and regulation of action potential firing rate. Predicted to be active in plasma membrane. Is expressed in early conceptus; heart; and secondary oocyte. Human ortholog(s) of this gene implicated in primary pulmonary hypertension. Orthologous to human KCNK3 (potassium two pore domain channel subfamily K member 3). PHENOTYPE: Mice homozygous for a null alleles exhibit decreased pH sensitivitive of action potential in serotonergic neurons. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
