| Primary Identifier | MGI:1100509 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 16527 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable S100 protein binding activity and potassium channel activity. Predicted to be involved in several processes, including cellular response to hypoxia; regulation of resting membrane potential; and stabilization of membrane potential. Predicted to act upstream of or within monoatomic ion transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in early conceptus; heart; and secondary oocyte. Human ortholog(s) of this gene implicated in primary pulmonary hypertension. Orthologous to human KCNK3 (potassium two pore domain channel subfamily K member 3). PHENOTYPE: Mice homozygous for a null alleles exhibit decreased pH sensitivitive of action potential in serotonergic neurons. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
