Primary Identifier | MGI:2140967 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 100732 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables microtubule plus-end binding activity. Involved in positive regulation of DNA-templated transcription and positive regulation of cyclin-dependent protein serine/threonine kinase activity. Located in cytoplasm; microtubule plus-end; and midbody. Colocalizes with microtubule. Orthologous to human MAPRE3 (microtubule associated protein RP/EB family member 3). PHENOTYPE: Mice homozygous for a conditional allele activated in endothelial cells fail to exhibit F2r agonist-induced vascular hyper-permeability. [provided by MGI curators] |