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Protein Coding Gene : Trim54 tripartite motif-containing 54
Primary Identifier  MGI:1889623 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  58522
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables microtubule binding activity. Acts upstream of or within negative regulation of microtubule depolymerization. Part of microtubule associated complex. Is expressed in several structures, including diaphragm; heart; lung; skeletal musculature; and trunk dermomyotome. Orthologous to human TRIM54 (tripartite motif containing 54).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal cardiac function but are prone to cardiac rupture after acute myocardial infarction. [provided by MGI curators]
  • synonyms:
  • MGI:1922577,
  • MGI:1925423,
  • RIKEN cDNA 4930486E09 gene,
  • 4930486E09Rik,
  • Trim54,
  • RIKEN cDNA 4930566I02 gene,
  • muscle-specific RING-finger protein,
  • tripartite motif-containing 54,
  • MuRF3,
  • ring finger protein 30,
  • 4930566I02Rik,
  • Rnf30
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