Primary Identifier | MGI:106065 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 14208 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables phosphoprotein phosphatase activity. Acts upstream of or within protein dephosphorylation and regulation of cell cycle. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Used to study schizophrenia. Orthologous to human PPM1G (protein phosphatase, Mg2+/Mn2+ dependent 1G). PHENOTYPE: Mice homozygous for a targeted mutation display perinatal lethality. Mice heterozygous for a targeted mutation display a decrease in prepulse inhibition. [provided by MGI curators] |