| Primary Identifier | MGI:2443635 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 193003 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables phosphatidylinositol bisphosphate binding activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and transmembrane transporter binding activity. Acts upstream of or within behavioral response to pain; positive regulation of cation channel activity; and response to heat. Located in plasma membrane. Is expressed in central nervous system; ganglia; gut; sensory organ; and trigeminal nerve. Orthologous to human PIRT (phosphoinositide interacting regulator of transient receptor potential channels). PHENOTYPE: Mice homozygous for a null allele exhibit decreased sensitivity to thermal and capsaicin nociception. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
