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Protein Coding Gene : Gpn1 GPN-loop GTPase 1
Primary Identifier  MGI:1921504 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  74254
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable GTPase activity. Predicted to be located in cytosol; mitochondrion; and nucleoplasm. Is expressed in embryo; sublingual gland primordium; and submandibular gland primordium. Orthologous to human GPN1 (GPN-loop GTPase 1).
PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality prior to organogenesis. In vitro, blastocysts fail to hatch from the zona pellucida and die after 3 days in culture. [provided by MGI curators]
  • synonyms:
  • GPN-loop GTPase 1,
  • MGI:2140891,
  • AI449615,
  • expressed sequence AI449615,
  • RIKEN cDNA 2410004J02 gene,
  • XPA binding protein 1,
  • Xab1,
  • Gpn1,
  • 2410004J02Rik
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