Primary Identifier | MGI:109194 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 22629 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables actin binding activity; protein domain specific binding activity; and transmembrane transporter binding activity. Involved in presynaptic modulation of chemical synaptic transmission. Acts upstream of or within intracellular protein transport and negative regulation of dendrite morphogenesis. Located in cytoplasm. Is active in cerebellar granule cell to Purkinje cell synapse and presynapse. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta). PHENOTYPE: Mice homozygous for a null allele exhibit normal oogenesis, in vitro oocyte maturation and in vivo breeding. [provided by MGI curators] |