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Protein Coding Gene : Chd3 chromodomain helicase DNA binding protein 3
Primary Identifier  MGI:1344395 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  216848
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0)

Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and histone binding activity. Acts upstream of or within chromatin organization. Part of NuRD complex. Is expressed in several structures, including 8-cell stage conceptus; blastocyst-stage conceptus; cerebral cortex; genitourinary system; and pancreas epithelium. Orthologous to human CHD3 (chromodomain helicase DNA binding protein 3).
PHENOTYPE: Homozygous knockout leads to increased embryonic lethality. [provided by MGI curators]
  • synonyms:
  • Mi-2 alpha,
  • RIKEN cDNA 2600010P09 gene,
  • Prp7,
  • Chd7,
  • AF020312,
  • cDNA sequence AF020312,
  • Chd3,
  • MGI:1934942,
  • Prp9-1,
  • 2600010P09Rik,
  • MGI:1919700,
  • chromodomain helicase DNA binding protein 7,
  • chromodomain helicase DNA binding protein 3
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1 Involved In Mutations

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0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

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Proteins

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Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

21 Pathways

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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