| Primary Identifier | MGI:2386643 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 231130 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable polyubiquitin modification-dependent protein binding activity and protein kinase binding activity. Involved in several processes, including cell surface receptor signaling pathway; pattern recognition receptor signaling pathway; and positive regulation of leukocyte activation. Acts upstream of or within negative regulation of canonical NF-kappaB signal transduction. Is active in cytoplasm. Orthologous to human TNIP2 (TNFAIP3 interacting protein 2). PHENOTYPE: Mice homozygous for a null allele have impaired IL-1 response and macrophage physiology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
