Primary Identifier | MGI:95801 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 14772 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable rhodopsin kinase activity. Predicted to be involved in G protein-coupled receptor internalization. Predicted to be located in several cellular components, including cytosol; dendrite; and neuronal cell body. Predicted to be active in cytoplasm. Is expressed in brain and testis. Human ortholog(s) of this gene implicated in essential hypertension. Orthologous to human GRK4 (G protein-coupled receptor kinase 4). PHENOTYPE: Mice heterozygous for a knock-out allele are viable, fertile and overtly normal. [provided by MGI curators] |