| Primary Identifier | MGI:107793 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 12933 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables phosphoprotein binding activity. Involved in regulation of postsynapse assembly and semaphorin-plexin signaling pathway. Located in several cellular components, including dendrite; growth cone; and neuronal cell body. Is active in postsynapse and presynapse. Is expressed in several structures, including genital tubercle of male; gut; nervous system; and retina. Orthologous to human CRMP1 (collapsin response mediator protein 1). PHENOTYPE: Mice homozygous for one knock-out allele show transient postnatal changes in granule cell proliferation, apoptosis and migration in cerebellum and delayed radial migration of cortical neurons in cerebral cortex. Homozygotes for another knock-out allele show reduced LTP and impaired spatial learning. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
