Primary Identifier | MGI:2684993 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 231162 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including cartilage homeostasis; chondrocyte differentiation; and regulation of DNA-templated transcription. Is expressed in several structures, including forelimb; gut; respiratory system; sensory organ; and skeleton. Orthologous to human CYTL1 (cytokine like 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased susceptibility to osteoarthritic cartilage destruction following destabilization of the medial meniscus surgery. [provided by MGI curators] |