| Primary Identifier | MGI:2388363 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 21906 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables proton channel activity. Involved in cellular response to insulin stimulus; negative regulation of type II interferon-mediated signaling pathway; and proton transmembrane transport. Acts upstream of or within detection of gravity and inner ear morphogenesis. Located in plasma membrane. Is expressed in several structures, including adrenal gland; inner ear; integumental system; stomach; and thymus. Orthologous to human OTOP1 (otopetrin 1). PHENOTYPE: Homozygous mutant mice display vestibular abnormalities associated with absent otoconia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
