Primary Identifier | MGI:99478 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 12425 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cholecystokinin receptor activity. Acts upstream of or within axonogenesis; forebrain development; and neuron migration. Predicted to be located in several cellular components, including endosome; nucleoplasm; and terminal bouton. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; genitourinary system; gut; and respiratory system. Human ortholog(s) of this gene implicated in obesity. Orthologous to human CCKAR (cholecystokinin A receptor). PHENOTYPE: Homozygous mutant mice cannot regulate core body temperature in response to changes in ambient temperature. [provided by MGI curators] |