Primary Identifier | MGI:1341296 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 21899 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables diacyl lipopeptide binding activity. Involved in several processes, including cellular response to oxidised low-density lipoprotein particle stimulus; positive regulation of biosynthetic process; and positive regulation of defense response. Part of Toll-like receptor 2-Toll-like receptor 6 protein complex. Is expressed in brain; cerebral cortex; embryo; and telencephalon. Human ortholog(s) of this gene implicated in aspergillosis; asthma; infective endocarditis; rhinitis; and tuberculosis. Orthologous to human TLR6 (toll like receptor 6). PHENOTYPE: Inactivation of this gene results in abnormal macrophage function. [provided by MGI curators] |