| Primary Identifier | MGI:1858216 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 53323 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin conjugating enzyme activity; ubiquitin protein ligase binding activity; and ubiquitin-ubiquitin ligase activity. Acts upstream of or within regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in cytoplasm; filopodium tip; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human UBE2K (ubiquitin conjugating enzyme E2 K). PHENOTYPE: Mice homozygous for a hypomorphic allele exhibit resistance to amyloid-beta neurotoxicity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
