Primary Identifier | MGI:2384294 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 245945 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables enzyme-substrate adaptor activity and mRNA 3'-UTR binding activity. Involved in 3'-UTR-mediated mRNA stabilization; cytidine to uridine editing; and positive regulation of interleukin-10 production. Acts upstream of or within hematopoietic progenitor cell differentiation. Located in nucleus. Is expressed in several structures, including brain ventricle and choroid plexus; genitourinary system; gut; sensory organ; and yolk sac. Orthologous to human RBM47 (RNA binding motif protein 47). PHENOTYPE: Mice homozygous for a gene-trapped allele exhibit partial prenatal lethality. Surviving adults are small and display impaired cytidine to uridine RNA editing. [provided by MGI curators] |