Primary Identifier | MGI:1343485 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 27784 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable NF-kappaB binding activity. Predicted to be involved in signal transduction. Predicted to be located in cytosol and nucleoplasm. Orthologous to human COMMD8 (COMM domain containing 8). PHENOTYPE: Mice homozygous for a conditional allele activated in B cells exhibit impaired B cell migration and humoral immune responses. [provided by MGI curators] |