| Primary Identifier | MGI:107726 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 20926 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable histone binding activity and nucleosome binding activity. Involved in regulation of isotype switching; regulation of muscle cell differentiation; and transcription elongation-coupled chromatin remodeling. Predicted to be located in nucleus. Predicted to be part of transcription elongation factor complex. Is expressed in several structures, including 4-8 cell stage conceptus; blastocyst-stage conceptus; brain; early embryo; and genitourinary system. Orthologous to human SUPT6H (SPT6 homolog, histone chaperone and transcription elongation factor). PHENOTYPE: Mice homozygous for a knock-out allele exhibit lethality during pre-implantation development. [provided by MGI curators] |