Primary Identifier | MGI:2180337 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 317755 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA sequestering activity; mRNA 3'-UTR binding activity; and molecular condensate scaffold activity. Involved in membraneless organelle assembly; oocyte maturation; and post-transcriptional regulation of gene expression. Is active in cytoplasm and intracellular membraneless organelle. Is expressed in early conceptus; ovary; and rib. Orthologous to human ZAR1 (zygote arrest 1). PHENOTYPE: Ovarian development and oogenesis are normal in homozygous null females; however, they are infertile due to a failure at the oocyte to embryo transition. [provided by MGI curators] |