Primary Identifier | MGI:98662 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 21682 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in adaptive immune response; cell surface receptor signaling pathway; and regulation of platelet activation. Located in cell-cell junction. Is expressed in several structures, including central nervous system; extraembryonic component; gut; placenta; and retina. Orthologous to human TEC (tec protein tyrosine kinase). PHENOTYPE: Mice homozygous for a knock-out allele exhibit a minor reduction in platetet aggregation in response to threshold concentrations of collagen-related peptide or collagen. [provided by MGI curators] |