Primary Identifier | MGI:1919563 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 72313 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in cell morphogenesis and neuron projection development. Predicted to be active in cell cortex and site of polarized growth. Is expressed in brain; exocrine system; retina nuclear layer; and tooth. Orthologous to human FRYL (FRY like transcription coactivator). PHENOTYPE: Most mice homozygous for a knock-out allele exhibit postnatal lethality and defects in kidney development; rare survivors display growth retardation, decreased body weight, and premature death associated with chronic hydronephrosis. [provided by MGI curators] |