Primary Identifier | MGI:1915345 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 68095 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in regulation of stem cell differentiation. Located in endosome. Is expressed in several structures, including cardiovascular system; early conceptus; gonad; limb bud; and trunk mesenchyme. Orthologous to human OCIAD1 (OCIA domain containing 1). PHENOTYPE: Mice homozygous for a null allele display increased hematopoitic cell numbers and proliferation, progressive increase in peripheral blood cells, decreased lifespans, splenomegaly, and increased sensitivity to radiation and chemical exposure. [provided by MGI curators] |