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Protein Coding Gene : Pdcl2 phosducin-like 2
Primary Identifier  MGI:1890655 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  79455
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in acrosome assembly. Acts upstream of or within sperm axoneme assembly. Located in endoplasmic reticulum. Orthologous to human PDCL2 (phosducin like 2).
PHENOTYPE: Mice homozygous for a null allele show male infertility, globozoospermia, abnormal acrosome biogenesis and lack of acrosomal cap formation, and sperm immobility and disrupted flagellum axonemes. [provided by MGI curators]
  • synonyms:
  • 1700016K07Rik,
  • MGI:1916664,
  • phosducin-like 2,
  • Mgcphlp,
  • 1700010B22Rik,
  • RIKEN cDNA 1700016K07 gene,
  • MGI:1913577,
  • Pdcl2,
  • RIKEN cDNA 1700010B22 gene
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