| Primary Identifier | MGI:2441950 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 319387 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium ion binding activity. Involved in several processes, including locomotion involved in locomotory behavior; response to cocaine; and synapse organization. Acts upstream of or within positive regulation of synapse assembly. Located in axon; cell-cell junction; and plasma membrane. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynaptic membrane. Is expressed in ductus deferens; epididymis; esophagus; and ileum. Used to study attention deficit hyperactivity disorder. Orthologous to human ADGRL3 (adhesion G protein-coupled receptor L3). PHENOTYPE: Mice homozygous for a gene trap allele exhibit increased dopamine and serotonine levels in the dorsal striatum, hyperactivity, increased stereotypic behavior and enhanced hyperactivity in response to cocaine. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
