Primary Identifier | MGI:99654 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 13839 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GPI-linked ephrin receptor activity. Involved in several processes, including ephrin receptor signaling pathway; nervous system development; and regulation of insulin secretion involved in cellular response to glucose stimulus. Acts upstream of or within cellular response to follicle-stimulating hormone stimulus and cellular response to forskolin. Located in adherens junction and cell periphery. Is expressed in several structures, including alimentary system; future midbrain; genitourinary system; nervous system; and sensory organ. Orthologous to human EPHA5 (EPH receptor A5). PHENOTYPE: Homozygous mutant mice are overtly normal but show abnormal retinal axon mapping. [provided by MGI curators] |