| Primary Identifier | MGI:99700 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 12617 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable centromeric DNA binding activity and identical protein binding activity. Predicted to be involved in attachment of mitotic spindle microtubules to kinetochore; kinetochore assembly; and spindle attachment to meiosis I kinetochore. Located in condensed chromosome, centromeric region and pericentric heterochromatin. Is expressed in primary spermatocyte. Human ortholog(s) of this gene implicated in CREST syndrome and liver cirrhosis. Orthologous to human CENPC (centromere protein C). PHENOTYPE: Homozygous mutation of this gene results in early embryonic lethality and mitotic abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
