| Primary Identifier | MGI:1913894 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 231380 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables FAT10 activating enzyme activity and ubiquitin activating enzyme activity. Involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Acts upstream of or within several processes, including dendritic spine development; learning; and limbic system development. Predicted to be active in cytoplasm and nucleus. Is expressed in cerebral cortex and gonad. Orthologous to human UBA6 (ubiquitin like modifier activating enzyme 6). PHENOTYPE: Mice homozygous for a knock-out allele exhibit early embryonic lethality. Mice homozygous for a conditional allele activated in neurons exhibit decreased weight, postnatal and premature lethality and altered social behavior and neuronal development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
