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Protein Coding Gene : Gnrhr gonadotropin releasing hormone receptor

Primary Identifier  MGI:95790 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  14715
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable gonadotropin-releasing hormone receptor activity and growth hormone-releasing hormone receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to hormone stimulus; and negative regulation of cell population proliferation. Predicted to be active in plasma membrane. Is expressed in several structures, including adenohypophysis; jaw; mandibular process; and ovary. Used to study hypogonadotropic hypogonadism 7 with or without anosmia. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 7 with or without anosmia. Orthologous to human GNRHR (gonadotropin releasing hormone receptor).
PHENOTYPE: Homozygous mutant mice display prepubescent internal reproductive tracts with hypogonadism and hypogonadotrophy. [provided by MGI curators]
  • synonyms:
  • Gnrhr,
  • gonadotropin releasing hormone receptor,
  • MGD-MRK-10209

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Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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2 Driver For