Primary Identifier | MGI:2442348 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 243083 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable serine-type endopeptidase activity. Acts upstream of or within establishment of skin barrier. Predicted to be located in cell surface. Orthologous to human TMPRSS11F (transmembrane serine protease 11F). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased transepidermal water loss and mortality at 37 degrees Celcius. [provided by MGI curators] |