| Primary Identifier | MGI:2443713 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 231386 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable N6-methyladenosine-containing RNA reader activity and mRNA binding activity. Involved in post-transcriptional regulation of gene expression. Acts upstream of or within several processes, including mRNA alternative polyadenylation; primary follicle stage; and regulation of alternative mRNA splicing, via spliceosome. Located in nucleus. Is expressed in brain; intestine; and liver. Orthologous to human YTHDC1 (YTH N6-methyladenosine RNA binding protein C1). PHENOTYPE: Mice homozygous for a null allele die between E8.5 and E11.5. Mice homozygous for a cconditional allele activated after embryonic development exhibit infertility with defects in spermatogenesis and oogenesis associated with RNA granules and altered transcription in oocytes. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
